Match events
Minute by minute- 1'1–0 Goal: Eljif Elmas Napoli
- 30' Red card: Mário Rui Napoli
- 41' Substitution: Kévin MalcuitOff: Lorenzo Insigne Napoli
- 44' Yellow card: Ezequiel Ponce Spartak Moscow
- 45' Substitution: Victor OsimhenOff: Andrea Petagna Napoli
- 45' Substitution: Frank AnguissaOff: Piotr Zielinski Napoli
- 45+1' Yellow card: Ruslan Litvinov Spartak Moscow
- 45+1' Substitution: Aleksandr SobolevOff: Ezequiel Ponce Spartak Moscow
- 45+8' Yellow card: Aleksandr Sobolev Spartak Moscow
- 45+8' Yellow card: Giovanni Di Lorenzo Napoli
- Half-time 1–0
- 55'1–1 Goal: Quincy Promes Spartak Moscow
- 65' Yellow card: Max Caufriez Spartak Moscow
- 65' Yellow card: Kalidou Koulibaly Napoli
- 73' Substitution: Mikhail IgnatovOff: Ruslan Litvinov Spartak Moscow
- 73' Substitution: Hirving LozanoOff: Matteo Politano Napoli
- 77' Yellow card: Ayrton Lucas Spartak Moscow
- 78' Yellow card: Fabián Ruiz Napoli
- 80'1–2 Goal: Mikhail IgnatovAssist: Ayrton Lucas Spartak Moscow
- 82' Substitution: Adam OunasOff: Eljif Elmas Napoli
- 82' Red card: Max Caufriez Spartak Moscow
- 84' Yellow card: Kostas Manolas Napoli
- 89' Substitution: Aleksandr LomovitskiOff: Zelimkhan Bakaev Spartak Moscow
- 89' Yellow card: Aleksandr Maksimenko Spartak Moscow
- 90'1–3 Goal: Quincy PromesAssist: Aleksandr Sobolev Spartak Moscow
- 90+4'2–3 Goal: Victor OsimhenAssist: Giovanni Di Lorenzo Napoli
- 90+10' Yellow card: Nail Umiarov Spartak Moscow
Line-ups
Confirmed
Napoli4-3-33-4-1-2Spartak Moscow
- 1 Meret
- 6 Rui
- 26 Koulibaly
- 44 Manolas
- 22A Di Lorenzo
- 2045' Zielinski
- 8 Ruiz
- 782' Elmas
- 2441' Insigne
- 3745' Petagna
- 2173' Politano
- 98 Maksimenko
- 14 Dzhikiya
- 2 Gigot
- 3 Caufriez
- 6A Lucas
- 18 Umiarov
- 6873' Litvinov
- 8 Moses
- 1089' Bakaev
- 24 Promes
- 945+1' Ponce
Napoli bench
- 9Victor Osimhen45'
- 99Frank Anguissa45'
- 2Kévin Malcuit41'
- 33Adam Ounas82'
- 11Hirving Lozano73'
Spartak Moscow bench
- 17Aleksandr Lomovitski89'
- 22Mikhail Ignatov73'
- 7Aleksandr Sobolev45+1'A