Match events
Minute by minute- 10' Yellow card: Juan Miranda Real Betis
- 45' Substitution: Álex MorenoOff: Juan Miranda Real Betis
- 45' Substitution: Diego LainezOff: Joaquín Real Betis
- Half-time 0–0
- 50' Yellow card: Lucas Alario Bayer Leverkusen
- 62' Yellow card: Edmond Tapsoba Bayer Leverkusen
- 64' Substitution: Sergio CanalesOff: Nabil Fekir Real Betis
- 69' Substitution: Florian WirtzOff: Amine Adli Bayer Leverkusen
- 69' Substitution: Patrik SchickOff: Lucas Alario Bayer Leverkusen
- 71' Yellow card: Germán Pezzella Real Betis
- 71' Yellow card: Piero Hincapié Bayer Leverkusen
- 71' Substitution: JuanmiOff: Aitor Ruibal Real Betis
- 75'1–0 Penalty goal: Borja Iglesias pen Real Betis
- 76' Substitution: Mitchel BakkerOff: Piero Hincapié Bayer Leverkusen
- 76' Substitution: PaulinhoOff: Karim Bellarabi Bayer Leverkusen
- 82'1–1 Goal: Robert Andrich Bayer Leverkusen
- 85' Substitution: Willian JoséOff: Borja Iglesias Real Betis
- 86' Yellow card: Moussa Diaby Bayer Leverkusen
- 90+1' Substitution: Exequiel PalaciosOff: Moussa Diaby Bayer Leverkusen
Line-ups
Confirmed
Real Betis4-2-3-14-2-3-1Bayer Leverkusen
- 25 Bravo
- 3345' Miranda
- 3 González
- 16 Pezzella
- 2 Montoya
- 14 Carvalho
- 21 Rodríguez
- 2471' Ruibal
- 864' Fekir
- 1745' Joaquín
- 985' Iglesias
- 1 Hradecky
- 3376' Hincapié
- 12 Tapsoba
- 4 Tah
- 30 Frimpong
- 8 Andrich
- 10 Demirbay
- 1990+1' Diaby
- 3169' Adli
- 3876' Bellarabi
- 1369' Alario
Real Betis bench
- 15Álex Moreno45'
- 10Sergio Canales64'
- 12Willian José85'
- 7Juanmi71'
- 20Diego Lainez45'
Bayer Leverkusen bench
- 25Exequiel Palacios90+1'
- 5Mitchel Bakker76'
- 14Patrik Schick69'
- 27Florian Wirtz69'
- 7Paulinho76'